RESUMEN
CONTEXT: Osteoporosis is a skeletal disorder characterized by low bone mass and microarchitectural deterioration of bone tissue. It may affect the craniomaxillofacial complex and result in less bone-implant contact. AIMS: The objective of this study was to measure the endosseous integration of titanium implants using the removal torque test in low-mineral density experimental animal models. MATERIALS AND METHODS: Thirty female New Zealand white rabbits were divided into two groups: control (n=14), sham-operated; and test (n=16), ovariectomized. All animals received 2.2 mm Χ 4.0 mm titanium implants in the right tibia, 120 days after ovariectomy or sham surgery. Animals were killed at 7 and 14 weeks of postimplant insertion, when implants were removed by reverse torque rotation using a digital torque meter. Statistical analysis used was Student's t-test. RESULTS AND CONCLUSION: At the 7-week period, the mean torque values for the control and test groups were 11.6 Ncm and 10.4 Ncm, respectively, with no statistical significance. Implant removal torque analysis showed statistically lower values (P < 0.05) for the test group at the 14-week period (control=16.7 Ncm and test=9.7 Ncm). The results of this study indicate that hormonal privacy compromise implants biomechanical performance.
Asunto(s)
Implantes Dentales , Materiales Dentales , Oseointegración/fisiología , Osteoporosis/fisiopatología , Titanio , Absorciometría de Fotón , Animales , Fenómenos Biomecánicos , Densidad Ósea/fisiología , Enfermedades Óseas Metabólicas/fisiopatología , Materiales Dentales/química , Remoción de Dispositivos , Modelos Animales de Enfermedad , Femenino , Ovariectomía , Conejos , Distribución Aleatoria , Estrés Mecánico , Tibia/cirugía , Factores de Tiempo , Titanio/química , TorqueRESUMEN
O objetivo deste estudo foi avaliar a atividade antimicrobiana do extrato da folha de Myrciaria cauliflora (Mart.) O. Berg., Myrtaceae (jabuticabeira) sobre: Streptococcus mitis (ATCC 903), Streptococcus mutans (ATCC 25175), Streptococcus sanguinis (ATCC 15300), Streptococcus oralis (ATCC 10557), Streptococcus salivarius (ATCC 7073) e Lactobacillus casei (ATCC 9595). A pesquisa foi realizada através de técnicas bacteriológicas laboriosas. Os ensaios foram realizados pelo método da diluição em meio sólido para a determinação da Concentração Inibitória Mínima (CIM). Os resultados obtidos foram transferidos para um banco de dados informatizado e calculados os parâmetros estatísticos mediante o emprego do programa SPSS versão 13.0. Utilizou-se, ao nível de 5 por cento de significância, o teste t-Student. Em estudo comparativo, foi determinada a CIM do digluconato de clorexidina a 0,12 por cento. O extrato de jabuticabeira formou halos de inibição variando de 10 a 18 mm de diâmetro e apresentou desempenho médio significativamente inferior em relação a clorexidina, na comparação do extrato bruto vs substância pura e nas concentrações 1:2 e 1:4. Conclui-se, que o extrato de Myrciaria cauliflora produziu uma significante atividade bacteriostática in vitro sobre as bactérias do biofilme dental, o que sugere a utilização dessa substância como meio alternativo e economicamente viável para o controle de afecções em Odontologia.
The aim of this study was to evaluate in vitro antimicrobial activity of Myrciaria cauliflora (Mart.) O. Berg., Myrtaceae leaves extract on: Streptococcus mitis (ATCC 903), Streptococcus mutans (ATCC 25175), Streptococcus sanguinis (ATCC 15300), Streptococcus oralis (ATCC 10557), Streptococcus salivarius (ATCC 7073) and Lactobacillus casei (ATCC 9595). The study was done using laborious bacteriological techniques. The assays were made through dilution in agar diffusion method in order to reach the Minimum Inhibitory Concentration (MIC) determination. The results obtained were transferred for database and had the statistics parameter calculated by SPSS program 13.0 version. The t-Student test was used with 5 percent of significance. In comparative study, the digluconate of chlorexidine (0,12 percent) was determinated. The leaf extract of Myrciaria cauliflora Berg. formed halos of inhibition oscillating between 10-18 mm of diameter and it showed middle performance significantly inferior in respect to digluconate of chlorexidine (0,12 percent), on the pure extract and in the concentrations 1:2 and 1:4. It follows that, the Myrciaria cauliflora Berg. extract produced a significative in vitro bactericidal activity on the former oral biofilm bacterias, that suggests the use of these substances as an economic and viable kind of alternative to the control of odontological diseases.
